Most Influential 2021: Arianna Simpson
The a16z general partner is investing in the future of the internet, Web 3.

Arianna Simpson’s trip to Zimbabwe in 2013 changed her life. But it was the experience of using Western Union, and the platform’s extortionary fees, to send money to the family she sponsored that changed her mind on crypto. Now a general partner at Andreessen Horowitz (a16z), she helps to manage the massively influential venture capital firm’s $2.2 billion crypto fund. Simpson previously spent time at Facebook and BitGo. She’s also run her own investment funds, Autonomous Partners, which focused on digital assets, and Crystal Towers Capital, which worked with early-stage startups.
The Complete List: CoinDesk’s Most Influential 2021

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Protocol Research: GoPlus Security

Що варто знати:
- As of October 2025, GoPlus has generated $4.7M in total revenue across its product lines. The GoPlus App is the primary revenue driver, contributing $2.5M (approx. 53%), followed by the SafeToken Protocol at $1.7M.
- GoPlus Intelligence's Token Security API averaged 717 million monthly calls year-to-date in 2025 , with a peak of nearly 1 billion calls in February 2025. Total blockchain-level requests, including transaction simulations, averaged an additional 350 million per month.
- Since its January 2025 launch , the $GPS token has registered over $5B in total spot volume and $10B in derivatives volume in 2025. Monthly spot volume peaked in March 2025 at over $1.1B , while derivatives volume peaked the same month at over $4B.
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Coinbase rolls out stock trading, prediction markets and more in bid to become the ‘Everything Exchange’

Coinbase is dramatically expanding the assets available to trade on its platform, including novel cryptocurrencies, perpetual futures, stocks and prediction markets, starting with Kalshi.
Що варто знати:
- Coinbase is expanding offerings on its platform, introducing hundreds of top stocks based on market cap, trading volume, etc, with plans to add thousands of additional stocks and ETFs over the coming months.
- Coinbase users will also be able to trade on the outcomes of real-world events like elections, sports, collectibles, and economic indicators, starting with Kalshi and more to be integrated over time.
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