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Bitcoin DeFi Gets Another Institutional Boost Through Anchorage Digital Custody

Anchorage Digital is opening institutional pathways into Bitcoin-native DeFi, providing a regulated gateway to BOB’s hybrid Bitcoin–Ethereum ecosystem.

Updated Nov 10, 2025, 8:26 a.m. Published Nov 7, 2025, 3:04 p.m.
Nathan McCauley, co-founder and CEO of Anchorage Digital at Consensus 2025.
Nathan McCauley, co-founder and CEO of Anchorage Digital at Consensus 2025. (CoinDesk)

What to know:

  • Anchorage Digital is opening institutional pathways into Bitcoin-native DeFi, providing a regulated gateway to BOB’s hybrid Bitcoin–Ethereum ecosystem.
  • The custody service provided by a U.S. federally-chartered bank could provide a boost for institutional participants seeking yield opportunities in BOB’s $250 million DeFi platform
  • This development marks a step in making bitcoin yield opportunities accessible to institutions seeking secure and compliant infrastructure.

Cryptocurrency bank Anchorage Digital is opening institutional pathways into Bitcoin-native decentralized finance (DeFi), providing a regulated gateway to BOB’s Bitcoin–Ethereum ecosystem.

The custody service provided by a U.S. federally-chartered bank could provide a boost for institutional participants seeking yield opportunities in BOB’s $250 million total value locked (TVL) DeFi platform, according to an emailed announcement shared with CoinDesk on Friday.

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Anchorage also holds a Major Payment Institution License (MPI) from the Monetary Authority of Singapore (MAS) and provides a self-custody wallet called Porto.

BOB ("Build on Bitcoin") describes itself as a hybrid layer-2 network combining the security of Bitcoin and the DeFi capabilities of Ethereum, whereby users can use their BTC holdings to access yield opportunities in the broader blockchain ecosystem with Ethereum as the entry point.

Anchorage providing custody services for BOB marks a step in making bitcoin yield opportunities accessible to institutions seeking secure and compliant infrastructure. The total value locked in true Bitcoin DeFi has surged from $200 million to over $8 billion in the past 18 months, according to DeFiLlama.

However, that still represents just 0.3% of bitcoin’s market capitalization. The expansion of regulated access points could catalyze greater growth as institutions look beyond passive BTC exposure to participate in yield-bearing DeFi activity.

"As smart contract capabilities mature, they unlock new applications that combine Bitcoin’s security with fresh utility, and open the door for institutions and holders to participate in meaningful ways," Nathan McCauley, CEO of Anchorage Digital, said in Friday's announcement.

Read More: Bitcoin-Holding Institutions Seeking Yield, DeFi Capabilities

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